Bioinformatics Tools for Screening of Antiparasitic Drugs
نویسندگان
چکیده
منابع مشابه
Bioinformatics Tools for Plant Genomics
The articles in this special issue reflect a convergence of developments in the fields of bioinformatics and plant genomics. Bioinformatics has its roots vaguely seated in the early 1980s, a time when personal computers began appearing in research laboratories and researchers began recognizing that those computers could be used as tools to organize, analyze and visualize their data. In the ensu...
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Anthelmintic discovery in the veterinary pharmaceutical industry has succeeded only through screening synthetic compounds and fermentation products against whole parasites in culture or in host animals. Following trends in the parent, and much larger, human pharmaceutical industry, many programs have been developed in the past 20 years to exploit mechanism-based screening strategies for the ide...
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There is no consensus on the benefits of treatment with any specific anthelminthic compound on muscle-stage trichinosis. A double-blind, placebo-controlled comparison was done of 3 antiparasitic drugs during an outbreak of trichinosis in Chiangrai Province, northern Thailand. Forty-six adults were randomized to receive 10 days of oral treatment with mebendazole (200 mg twice a day), thiabendazo...
متن کاملNatural Products as potential antiparasitic drugs
Pharmaceutical research in natural products represents a major strategy for discovering and developing new drugs. The use of medicinal plants for the treatment of parasitic diseases is well known and documented since ancient times e.g. by the use of Cinchona succiruba (Rubiaceae) as an antimalarial. This chapter provides a comprehensive review of the latest results in the field of antiparasitic...
متن کاملEvaluation of ontology development tools for bioinformatics
Ontologies are being used nowadays in many areas, including bioinformatics. To assist users in developing and maintaining ontologies a number of tools have been developed. In this paper we compare four such tools, Protégé-2000, Chimaera, DAG-Edit and OilEd. As test ontologies we have used ontologies from the Gene Ontology Consortium. No system is preferred in all situations, but each system has...
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ژورنال
عنوان ژورنال: Current Drug Targets
سال: 2009
ISSN: 1389-4501
DOI: 10.2174/138945009787581122